منابع مشابه
Allopurinol Induced DRESS Syndrome.
A 45 years old female on allopurinol for 3 months presented with itching, rash, facial oedema and eosinophilia with hepatic and renal dysfunction. Skin biopsy revealed interface dermatitis, suggesting the diagnosis of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome.
متن کاملAllopurinol-induced DRESS syndrome.
Hyperuricemia is present in approximately 5% of the population, the vast majority of whom are asymptomatic and at no clinical risk. Complications, including renal calculi, uric acid nephropathy and gout, occur in a small proportion of patients. Allopurinol, an analog of hypoxanthine, has been widely used in clinical practice for over 30 years for the treatment of hyperuricemia and gout. Two per...
متن کاملAllopurinol-induced severe cutaneous adverse reactions.
In their article entitled ‘Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin’, Chung and colleagues elegantly investigated the factors associated with severe cutaneous adverse reactions (SCAR) in patients taking allopurinol as antihyperuricaemic agent and found that impai...
متن کاملAllopurinol Induced Steven- Jonson Syndrome: Case Report
Adverse drug reactions occur in about 0.3 to 7% of all hospital admissions and are associated with high morbidity and mortality. Their presentation varies from mild rashes to severe reactions such as StevensJohnson syndrome (SJS). Steven Johnson's Syndrome is rare, serious systemic disorder involving the skin and mucous membranes. Stevens-Johnson syndrome is commonly associated with adverse dru...
متن کاملAllopurinol-induced DRESS syndrome mimicking biliary obstruction
An 84-year-old man was admitted to our hospital with fever, jaundice, and itching. He had been diagnosed previously with chronic renal failure and diabetes, and had been taking allopurinol medication for 2 months. A physical examination revealed that he had a fever (38.8℃), jaundice, and a generalized maculopapular rash. Azotemia, eosinophilia, atypical lymphocytosis, elevation of liver enzymes...
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ژورنال
عنوان ژورنال: Case Reports
سال: 2012
ISSN: 1757-790X
DOI: 10.1136/bcr-2012-007283